HSPMdb Accession NoHSPMDB001642
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name353
IUPAC Name4-{12-oxo-9-thia-2-azatetracyclo[9.7.0.0³,?.0¹³,¹?]octadeca-1(11),3(8),4,6,13(18),14,16-heptaen-10-yl}phenyl formate
SMILESO=COc1ccc(cc1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001642

353

Physicochemical Properties