HSPMdb Accession NoHSPMDB001640
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name366
IUPAC Name2,3-Dichloro-5,11-dihydro-11-(3-hydroxyphenyl)-12H-benzo[b]indeno[1,2- e][1,4]thiazepin-12-one
SMILESOc1cccc(c1)C2Sc3ccccc3NC4=C2C(=O)c5cc(Cl)c(Cl)cc45
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001640

366

Physicochemical Properties