HSPMdb Accession NoHSPMDB001638
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name376
IUPAC NameN-{2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethyl}-2-(3-hydroxyphenyl)-17-oxo-2?³-thia-9-azatetracyclo[8.7.0.0³,?.0¹¹,¹?]heptadeca-1(10),3(8),4,6,11,13,15-heptaene-14-carboxamide
SMILESC(CC#C)C1(N=N1)CCNC(=O)C1=CC=C2C=3NC=4C=CC=CC4[S](C3C(C2=C1)=O)C1=CC(=CC=C1)O
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001638

376

Physicochemical Properties