HSPMdb Accession No | HSPMDB001638 |
PMID | 28906057 |
Target | Hsp100 |
HSP Name | ClpX |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 376 |
IUPAC Name | N-{2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethyl}-2-(3-hydroxyphenyl)-17-oxo-2?³-thia-9-azatetracyclo[8.7.0.0³,?.0¹¹,¹?]heptadeca-1(10),3(8),4,6,11,13,15-heptaene-14-carboxamide |
SMILES | C(CC#C)C1(N=N1)CCNC(=O)C1=CC=C2C=3NC=4C=CC=CC4[S](C3C(C2=C1)=O)C1=CC(=CC=C1)O |
Class | Synthetic chemical compounds |
IC50 (µM) | <50 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (GFP) |
Disease | Bacterial infection |