HSPMdb Accession NoHSPMDB001633
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name358
IUPAC Name5,11-Dihydro-11-(3-bromo-5-hydroxyphenyl)-12H-benzo[b]indeno[1,2-e][1,4]thiazepin12-one
SMILESOc1cc(Br)cc(c1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001633

358

Physicochemical Properties