HSPMdb Accession NoHSPMDB001622
PMID21944755
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityBinding affinity
Compound NameACP1b
IUPAC NameN-{1-[(2-chlorophenyl)sulfanyl]propan-2-yl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide
SMILESCC(CSC1=CC=CC=C1Cl)NC(=O)C(C)(C)S(=O)(=O)C1=CC=C(C=N1)C(F)(F)F
ClassLOPAC 1280 , Prestwick, SPECTRUM, Maybridge, and Chembridge DIVERSet
Kd (µM)3.2, n=16.1
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayIsothermal titration calorimetry (ITC)
DiseaseBacterial infection

Structure



HSPMDB001622

ACP1b

Physicochemical Properties