HSPMdb Accession NoHSPMDB001535
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name12
IUPAC Name(3Z)-5-Bromo-3-[3-(3-methoxypropyl)-4-oxo-2-thioxo-1,3- thiazolidin-5-ylidene]-1,3-dihydro-2H-indol-2-one
SMILESCOCCCN1C(=S)SC(/C1=O)=C/2C(=O)Nc3ccc(Br)cc23
ClassMyriaScreen diversity collection
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001535

12

Physicochemical Properties