HSPMdb Accession No | HSPMDB001535 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 12 |
IUPAC Name | (3Z)-5-Bromo-3-[3-(3-methoxypropyl)-4-oxo-2-thioxo-1,3- thiazolidin-5-ylidene]-1,3-dihydro-2H-indol-2-one |
SMILES | COCCCN1C(=S)SC(/C1=O)=C/2C(=O)Nc3ccc(Br)cc23 |
Class | MyriaScreen diversity collection |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |