HSPMdb Accession No | HSPMDB001533 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 10 |
IUPAC Name | 1-Ethyl-4-hydroxy-N-(3-hydroxyphenyl)-2-oxo-1,2-dihydro-3- quinolinecarboxamide |
SMILES | CCN1C(=O)C(=C(O)c2ccccc12)C(=O)Nc3cccc(O)c3 |
Class | MyriaScreen diversity collection |
IC50 (µM) | 65 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |