HSPMdb Accession NoHSPMDB001533
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name10
IUPAC Name1-Ethyl-4-hydroxy-N-(3-hydroxyphenyl)-2-oxo-1,2-dihydro-3- quinolinecarboxamide
SMILESCCN1C(=O)C(=C(O)c2ccccc12)C(=O)Nc3cccc(O)c3
ClassMyriaScreen diversity collection
IC50 (µM)65
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001533

10

Physicochemical Properties