HSPMdb Accession NoHSPMDB001532
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name9
IUPAC Name2-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2- thioxo-1,3-thiazolidin-3-yl]-3-methylbutanoic acid
SMILESCC(C)C(N1C(=S)SC(/C1=O)=C/2C(=O)Nc3ccc(Br)cc23)C(O)=O
ClassMyriaScreen diversity collection
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001532

9

Physicochemical Properties