HSPMdb Accession No | HSPMDB001532 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 9 |
IUPAC Name | 2-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2- thioxo-1,3-thiazolidin-3-yl]-3-methylbutanoic acid |
SMILES | CC(C)C(N1C(=S)SC(/C1=O)=C/2C(=O)Nc3ccc(Br)cc23)C(O)=O |
Class | MyriaScreen diversity collection |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |