HSPMdb Accession No | HSPMDB001531 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 8 |
IUPAC Name | 2-(4-Chloro-5-methyl-3-nitro-1H-pyrazol-1-yl)-N-[3-(2,4- dichlorophenoxy)-5-nitrophenyl]acetamide |
SMILES | Cc1n(CC(=O)Nc2cc(Oc3ccc(Cl)cc3Cl)cc(c2)[N+]([O-])=O)nc(c1Cl)[N+]([O-])=O |
Class | MyriaScreen diversity collection |
IC50 (µM) | >100 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |