HSPMdb Accession NoHSPMDB001531
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name8
IUPAC Name2-(4-Chloro-5-methyl-3-nitro-1H-pyrazol-1-yl)-N-[3-(2,4- dichlorophenoxy)-5-nitrophenyl]acetamide
SMILESCc1n(CC(=O)Nc2cc(Oc3ccc(Cl)cc3Cl)cc(c2)[N+]([O-])=O)nc(c1Cl)[N+]([O-])=O
ClassMyriaScreen diversity collection
IC50 (µM)>100
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001531

8

Physicochemical Properties