HSPMdb Accession NoHSPMDB001529
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name6
IUPAC Name2-{[(3,4-Dichlorophenyl)carbamothioyl]sulfanyl}ethyl phenylcarbamate
SMILESClc1ccc(NC(=S)SCCOC(=O)Nc2ccccc2)cc1Cl
ClassMyriaScreen diversity collection
IC50 (µM)20
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001529

6

Physicochemical Properties