HSPMdb Accession No | HSPMDB001528 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 5 |
IUPAC Name | (4Z)-1-(4-Chlorophenyl)-4-{4-[(4-fluorobenzyl)oxy]-3- methoxybenzylidene}-3,5-pyrazolidinedione |
SMILES | COc1cc(ccc1OCc2ccc(F)cc2)/C=C3/C(=O)NN(C3=O)c4ccc(Cl)cc4 |
Class | MyriaScreen diversity collection |
IC50 (µM) | 7.5 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |