HSPMdb Accession No | HSPMDB001525 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 2 |
IUPAC Name | (5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-3-phenyl1,3-thiazolidine-2,4-dione |
SMILES | Brc1ccc2NC(=O)C(=C/3SC(=O)N(C3=O)c4ccccc4)/c2c1 |
Class | MyriaScreen diversity collection |
IC50 (µM) | 30 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |