HSPMdb Accession NoHSPMDB001525
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name2
IUPAC Name(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-3-phenyl1,3-thiazolidine-2,4-dione
SMILESBrc1ccc2NC(=O)C(=C/3SC(=O)N(C3=O)c4ccccc4)/c2c1
ClassMyriaScreen diversity collection
IC50 (µM)30
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001525

2

Physicochemical Properties