HSPMdb Accession NoHSPMDB001524
PMID23961953
TargetHsp100
HSP NameClpB
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of chaperone activity
Compound Name1
IUPAC Name(3Z)-3-[3-(4-Chlorophenyl)-4-oxo-2-thioxo-1,3-thiazolidin-5- ylidene]-5-nitro-1,3-dihydro-2H-indol-2-one
SMILES[O-][N+](=O)c1ccc2NC(=O)\C(=C3/SC(=S)N(C3=O)c4ccc(Cl)cc4)c2c1
ClassMyriaScreen diversity collection
IC50 (µM)10
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayLuciferase aggregate reactivation assay
DiseaseBacterial infection

Structure



HSPMDB001524

1

Physicochemical Properties