HSPMdb Accession No | HSPMDB001524 |
PMID | 23961953 |
Target | Hsp100 |
HSP Name | ClpB |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of chaperone activity |
Compound Name | 1 |
IUPAC Name | (3Z)-3-[3-(4-Chlorophenyl)-4-oxo-2-thioxo-1,3-thiazolidin-5- ylidene]-5-nitro-1,3-dihydro-2H-indol-2-one |
SMILES | [O-][N+](=O)c1ccc2NC(=O)\C(=C3/SC(=S)N(C3=O)c4ccc(Cl)cc4)c2c1 |
Class | MyriaScreen diversity collection |
IC50 (µM) | 10 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Luciferase aggregate reactivation assay |
Disease | Bacterial infection |