HSPMdb Accession NoHSPMDB001498
PMID25299406
TargetHsp100
HSP NameHsp104
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameMerbromin
IUPAC Name(2',7'-dibromo-3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-4'-yl)mercury(1+)
SMILESOc1cc2Oc3c([Hg+])c(O)c(Br)cc3C4(OC(=O)c5ccccc45)c2cc1Br
ClassNIH, Spectrum, and Hit finder collection
% Enzymatic Inhibition/Fold Change21.17% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001498

Merbromin

Physicochemical Properties