HSPMdb Accession NoHSPMDB001497
PMID25299406
TargetHsp100
HSP NameHsp104
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameEpigallocatechin 3,5-digallate
IUPAC Name(2R,3R)-7-hydroxy-5-(3,4,5-trihydroxybenzoyl)oxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
SMILESOC=1C=C(C(=O)O[C@H]2[C@H](OC3=CC(=CC(=C3C2)OC(C2=CC(=C(C(=C2)O)O)O)=O)O)C2=CC(=C(C(=C2)O)O)O)C=C(C1O)O
ClassNIH, Spectrum, and Hit finder collection
% Enzymatic Inhibition/Fold Change21.88% at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001497

Epigallocatechin 3,5-digallate

Physicochemical Properties