HSPMdb Accession No | HSPMDB001497 |
PMID | 25299406 |
Target | Hsp100 |
HSP Name | Hsp104 |
Organism | Yeast |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | Epigallocatechin 3,5-digallate |
IUPAC Name | (2R,3R)-7-hydroxy-5-(3,4,5-trihydroxybenzoyl)oxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
SMILES | OC=1C=C(C(=O)O[C@H]2[C@H](OC3=CC(=CC(=C3C2)OC(C2=CC(=C(C(=C2)O)O)O)=O)O)C2=CC(=C(C(=C2)O)O)O)C=C(C1O)O |
Class | NIH, Spectrum, and Hit finder collection |
% Enzymatic Inhibition/Fold Change | 21.88% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |