HSPMdb Accession No | HSPMDB001494 |
PMID | 25299406 |
Target | Hsp100 |
HSP Name | Hsp104 |
Organism | Yeast |
Localization | Cytosol |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | Methacycline hydrochloride |
IUPAC Name | 4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide hydrochloride |
SMILES | Cl.CN(C1C(C(=C(C2(C(C3=C(C4=C(C=CC=C4C(C3C(C12)O)=C)O)O)=O)O)O)C(=O)N)=O)C |
Class | NIH, Spectrum, and Hit finder collection |
% Enzymatic Inhibition/Fold Change | 33.33% at 10 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | ATPase assay |