HSPMdb Accession NoHSPMDB001490
PMID25299406
TargetHsp100
HSP NameHsp104
OrganismYeast
LocalizationCytosol
Enzymatic activityInhibition of ATPase activity
Compound NameGossypol-acetic acid complex
IUPAC Name7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
SMILESC(=O)C=1C(=C(C(=C2C=C(C(=C(C12)O)C1=C(C=C2C(=C(C(=C(C2=C1O)C=O)O)O)C(C)C)C)C)C(C)C)O)O
ClassNIH, Spectrum, and Hit finder collection
% Enzymatic Inhibition/Fold Change47.92%at 10 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayATPase assay

Structure



HSPMDB001490

Gossypol-acetic acid complex

Physicochemical Properties