HSPMdb Accession No | HSPMDB001482 |
PMID | 20481474 |
Target | Hsp70 |
HSP Name | DnaK |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Activation of chaperone activity |
Compound Name | 115-7c |
IUPAC Name | 4-{5-[(benzyloxy)carbonyl]-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}butanoic acid |
SMILES | CC1=C(C(NC(=O)N1CCCC(O)=O)C1=C(Cl)C=C(Cl)C=C1)C(=O)OCC1=CC=CC=C1 |
Class | Dihydropyrimidine derivative |
% Enzymatic Inhibition/Fold Change | 2 fold at 1 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Refolding assay (luciferase) |