HSPMdb Accession NoHSPMDB001443
PMID25935385
TargetHsp70
HSP NameDnaK:DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name47
IUPAC NameN-(2-chlorobenzyl)-1-(2-methoxypyrimidin-4-yl)-N-methylpiperidin-4-amine
SMILESCOc1nccc(n1)N2CCC(CC2)N(C)Cc3ccccc3Cl
ClassPiperidine derivative
% Enzymatic Inhibition/Fold Change6.11% at 200 uM
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseBacterial infection

Structure



HSPMDB001443

47

Physicochemical Properties