HSPMdb Accession No | HSPMDB001441 |
PMID | 25935385 |
Target | Hsp70 |
HSP Name | DnaK:DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 43 |
IUPAC Name | N-(2,6-dichlorobenzyl)-N-methyl-1-(2-(methylthio)pyrimidin-4-yl)piperidin-4-amine |
SMILES | CSc1nccc(n1)N2CCC(CC2)N(C)Cc3c(Cl)cccc3Cl |
Class | Piperidine derivative |
% Enzymatic Inhibition/Fold Change | 12.81% at 200 uM |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | ATPase assay |
Disease | Bacterial infection |