HSPMdb Accession NoHSPMDB001437
PMID25935385
TargetHsp70
HSP NameDnaK:DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name36
IUPAC Name4-((Methyl(1-(2-(methylthio)pyrimidin-4-yl)piperidin-4-yl)amino)methyl) benzonitrile
SMILESCSc1nccc(n1)N2CCC(CC2)N(C)Cc3ccc(cc3)C#N
ClassPiperidine derivative
% Enzymatic Inhibition/Fold Change8.14% at 200 uM
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseBacterial infection

Structure



HSPMDB001437

36

Physicochemical Properties