HSPMdb Accession No | HSPMDB001435 |
PMID | 25935385 |
Target | Hsp70 |
HSP Name | DnaK:DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 22 |
IUPAC Name | 4-(((1-((2-Chlorothiazol-5-yl)methyl)piperidin-4-yl)(methyl)amino)methyl) benzonitrile |
SMILES | CN(Cc1ccc(cc1)C#N)C2CCN(CC2)Cc3sc(Cl)nc3 |
Class | Piperidine derivative |
% Enzymatic Inhibition/Fold Change | 11.28% at 200 uM |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | ATPase assay |
Disease | Bacterial infection |