HSPMdb Accession NoHSPMDB001433
PMID25935385
TargetHsp70
HSP NameDnaK:DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name16
IUPAC NameN-(3,4-dichlorobenzyl)-N-methyl-1-((2-(methylthio)thiazol-5-yl)methyl)piperidin-4-amine
SMILESCSc1sc(CN2CCC(CC2)N(C)Cc3ccc(Cl)c(Cl)c3)cn1
ClassPiperidine derivative
% Enzymatic Inhibition/Fold Change10.74% at 200 uM
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseBacterial infection

Structure



HSPMDB001433

16

Physicochemical Properties