HSPMdb Accession NoHSPMDB001432
PMID25935385
TargetHsp70
HSP NameDnaK:DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name12
IUPAC NameN-methyl-N-(4-methylbenzyl)-1-((2-(methylthio)thiazol-5-yl)methyl)piperidin-4-amine
SMILESCSc1sc(CN2CCC(CC2)N(C)Cc3ccc(C)cc3)cn1
ClassPiperidine derivative
% Enzymatic Inhibition/Fold Change10.59% at 200 uM
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseBacterial infection

Structure



HSPMDB001432

12

Physicochemical Properties