HSPMdb Accession NoHSPMDB001431
PMID25935385
TargetHsp70
HSP NameDnaK:DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name8
IUPAC NameN-(2,4-dichlorobenzyl)-1-((2-ethoxythiazol-5-yl)methyl)-N-methylpiperidin-4-amine
SMILESCCOc1sc(CN2CCC(CC2)N(C)Cc3ccc(Cl)cc3Cl)cn1
ClassPiperidine derivative
% Enzymatic Inhibition/Fold Change4.5% at 200 uM
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseBacterial infection

Structure



HSPMDB001431

8

Physicochemical Properties