HSPMdb Accession No | HSPMDB001431 |
PMID | 25935385 |
Target | Hsp70 |
HSP Name | DnaK:DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 8 |
IUPAC Name | N-(2,4-dichlorobenzyl)-1-((2-ethoxythiazol-5-yl)methyl)-N-methylpiperidin-4-amine |
SMILES | CCOc1sc(CN2CCC(CC2)N(C)Cc3ccc(Cl)cc3Cl)cn1 |
Class | Piperidine derivative |
% Enzymatic Inhibition/Fold Change | 4.5% at 200 uM |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | ATPase assay |
Disease | Bacterial infection |