HSPMdb Accession No | HSPMDB001430 |
PMID | 25935385 |
Target | Hsp70 |
HSP Name | DnaK:DnaJ |
Organism | Bacteria |
Localization | Cytosol and membrane |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | 4 |
IUPAC Name | 4-(((1-((2-Ethoxythiazol-5-yl)methyl)piperidin-4-yl)(methyl)amino)methyl) benzonitrile |
SMILES | CCOc1sc(CN2CCC(CC2)N(C)Cc3ccc(cc3)C#N)cn1 |
Class | Piperidine derivative |
% Enzymatic Inhibition/Fold Change | 5.49% at 200 uM |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | ATPase assay |
Disease | Bacterial infection |