HSPMdb Accession NoHSPMDB001430
PMID25935385
TargetHsp70
HSP NameDnaK:DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of ATPase activity
Compound Name4
IUPAC Name4-(((1-((2-Ethoxythiazol-5-yl)methyl)piperidin-4-yl)(methyl)amino)methyl) benzonitrile
SMILESCCOc1sc(CN2CCC(CC2)N(C)Cc3ccc(cc3)C#N)cn1
ClassPiperidine derivative
% Enzymatic Inhibition/Fold Change5.49% at 200 uM
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssayATPase assay
DiseaseBacterial infection

Structure



HSPMDB001430

4

Physicochemical Properties