HSPMdb Accession NoHSPMDB001429
PMID25935385
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name56
IUPAC NameN-(4-fluorobenzyl)-1-(2-methoxypyrimidin-4-yl)-N-methylpiperidin-4-amine
SMILESCOc1nccc(n1)N2CCC(CC2)N(C)Cc3ccc(F)cc3
ClassPiperidine derivative
Kd (µM)2.811
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssaySurface plasmon resonance (SPR)
DiseaseCancer

Structure



HSPMDB001429

56

Physicochemical Properties