HSPMdb Accession No | HSPMDB001428 |
PMID | 25935385 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Binding affinity |
Compound Name | 36 |
IUPAC Name | 4-((Methyl(1-(2-(methylthio)pyrimidin-4-yl)piperidin-4-yl)amino)methyl) benzonitrile |
SMILES | CSc1nccc(n1)N2CCC(CC2)N(C)Cc3ccc(cc3)C#N |
Class | Piperidine derivative |
Kd (µM) | 0.2463 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | Surface plasmon resonance (SPR) |
Disease | Cancer |