HSPMdb Accession NoHSPMDB001428
PMID25935385
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name36
IUPAC Name4-((Methyl(1-(2-(methylthio)pyrimidin-4-yl)piperidin-4-yl)amino)methyl) benzonitrile
SMILESCSc1nccc(n1)N2CCC(CC2)N(C)Cc3ccc(cc3)C#N
ClassPiperidine derivative
Kd (µM)0.2463
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssaySurface plasmon resonance (SPR)
DiseaseCancer

Structure



HSPMDB001428

36

Physicochemical Properties