HSPMdb Accession NoHSPMDB001427
PMID25935385
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name35
IUPAC NameN-(4-fluorobenzyl)-N-methyl-1-(2-(methylthio)pyrimidin-4-yl)piperidin-4-amine
SMILESCSc1nccc(n1)N2CCC(CC2)N(C)Cc3ccc(F)cc3
ClassPiperidine derivative
Kd (µM)2.045
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssaySurface plasmon resonance (SPR)
DiseaseCancer

Structure



HSPMDB001427

35

Physicochemical Properties