HSPMdb Accession NoHSPMDB001426
PMID25935385
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name14
IUPAC NameN-(3-chlorobenzyl)-N-methyl-1-((2-(methylthio)thiazol-5-yl)methyl)piperidin-4-amine
SMILESCSc1sc(CN2CCC(CC2)N(C)Cc3cccc(Cl)c3)cn1
ClassPiperidine derivative
Kd (µM)2.454
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssaySurface plasmon resonance (SPR)
DiseaseCancer

Structure



HSPMDB001426

14

Physicochemical Properties