HSPMdb Accession NoHSPMDB001425
PMID25935385
TargetHsp70
HSP NameHsp70
OrganismHuman
LocalizationCytosol
Enzymatic activityBinding affinity
Compound Name12
IUPAC NameN-methyl-N-(4-methylbenzyl)-1-((2-(methylthio)thiazol-5-yl)methyl)piperidin-4-amine
SMILESCSc1sc(CN2CCC(CC2)N(C)Cc3ccc(C)cc3)cn1
ClassPiperidine derivative
Kd (µM)0.1999
Site of InteractionNucleotide binding domain (allosteric site)
Type of Enzymatic AssaySurface plasmon resonance (SPR)
DiseaseCancer

Structure



HSPMDB001425

12

Physicochemical Properties