HSPMdb Accession No | HSPMDB001424 |
PMID | 25935385 |
Target | Hsp70 |
HSP Name | Hsp70 |
Organism | Human |
Localization | Cytosol |
Enzymatic activity | Binding affinity |
Compound Name | VER-155008 |
IUPAC Name | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile |
SMILES | Nc1ncnc2n([C@@H]3O[C@H](COCc4ccc(cc4)C#N)[C@@H](O)[C@H]3O)c(NCc5ccc(Cl)c(Cl)c5)nc12 |
Class | Piperidine derivative |
Kd (µM) | 0.206 |
Site of Interaction | Nucleotide binding domain (allosteric site) |
Type of Enzymatic Assay | Surface plasmon resonance (SPR) |
Disease | Cancer |