| HSPMdb Accession No | HSPMDB001377 |
| PMID | 25935385 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 21 |
| IUPAC Name | 2-(((1-((2-Chlorothiazol-5-yl)methyl)piperidin-4-yl)(methyl)amino)methyl) benzonitrile |
| SMILES | CN(Cc1ccccc1C#N)C2CCN(CC2)Cc3sc(Cl)nc3 |
| Class | Piperidine derivative |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Percentage Cell Growth Inhibition | 8.2 at 5 uM |
| Cellular assay | Luminescence based viability assay |
| Cellular Model | MDA-MB-453 |
| Disease | Cancer |
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