HSPMdb Accession NoHSPMDB001175
PMID25935385
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name23
IUPAC Name1-((2-Chlorothiazol-5-yl)methyl)-N-(4-fluorobenzyl)-N-methylpiperidin-4-amine
SMILESCN(Cc1ccc(F)cc1)C2CCN(CC2)Cc3sc(Cl)nc3
ClassPiperidine derivative
Site of InteractionNucleotide binding domain (allosteric site)
Percentage Cell Growth Inhibition-1.3
Cellular assayLuminescence based viability assay
Cellular ModelMDA-MB-361
DiseaseCancer

Structure



HSPMDB001175

23

Physicochemical Properties