| HSPMdb Accession No | HSPMDB001063 |
| PMID | 25935385 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 43 |
| IUPAC Name | N-(2,6-dichlorobenzyl)-N-methyl-1-(2-(methylthio)pyrimidin-4-yl)piperidin-4-amine |
| SMILES | CSc1nccc(n1)N2CCC(CC2)N(C)Cc3c(Cl)cccc3Cl |
| Class | Piperidine derivative |
| IC50 (µM) | 0.78 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Percentage Cell Growth Inhibition | 73.1 at 5 uM |
| Cellular assay | Luminescence based viability assay |
| Cellular Model | BT474 |
| Disease | Cancer |
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