HSPMdb Accession NoHSPMDB001013
PMID25148104
TargetHsp70
HSP NameHsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound NamePET-16
IUPAC Nametriphenyl(phenylethynyl)phosphonium bromide
SMILES[Br-].C1(=CC=CC=C1)[P+](C#CC1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
Class2-phenylethyenesulfonamide (PES) derivative
Kd (µM)3.8
Site of InteractionC-terminal domain
Type of Enzymatic AssayIsothermal Titration Calorimetry (ITC)
DiseaseCancer

Structure



HSPMDB001013

PET-16

Physicochemical Properties