HSPMdb Accession NoHSPMDB001012
PMID25148104
TargetHsp70
HSP NameHsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Enzymatic activityBinding affinity
Compound Name2-phenylethyenesulfonamide (PES)
IUPAC Name2-phenylethynesulfonamide
SMILESC1=CC=C(C=C1)C#CS(=O)(=O)N
Kd (µM)5.7
Site of InteractionC-terminal domain
Type of Enzymatic AssayIsothermal Titration Calorimetry (ITC)
DiseaseCancer

Structure



HSPMDB001012

2-phenylethyenesulfonamide (PES)

Physicochemical Properties