HSPMdb Accession NoHSPMDB001011
PMID25148104
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound NamePET-16
IUPAC Nametriphenyl(phenylethynyl)phosphonium bromide
SMILES[Br-].C1(=CC=CC=C1)[P+](C#CC1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
Class2-phenylethyenesulfonamide (PES) derivative
Site of InteractionC-terminal domain
Percentage Cell Growth Inhibition100% at 10 um
Cellular assayMTT viability assay
Cellular ModelA875
DiseaseCancer

Structure



HSPMDB001011

PET-16

Physicochemical Properties