HSPMdb Accession NoHSPMDB001010
PMID25148104
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name2-phenylethyenesulfonamide (PES)
IUPAC Name2-phenylethynesulfonamide
SMILESC1=CC=C(C=C1)C#CS(=O)(=O)N
Site of InteractionC-terminal domain
Percentage Cell Growth Inhibition90% at 10 uM
Cellular assayMTT viability assay
Cellular ModelA875
DiseaseCancer

Structure



HSPMDB001010

2-phenylethyenesulfonamide (PES)

Physicochemical Properties