HSPMdb Accession No | HSPMDB001010 |
PMID | 25148104 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | 2-phenylethyenesulfonamide (PES) |
IUPAC Name | 2-phenylethynesulfonamide |
SMILES | C1=CC=C(C=C1)C#CS(=O)(=O)N |
Site of Interaction | C-terminal domain |
Percentage Cell Growth Inhibition | 90% at 10 uM |
Cellular assay | MTT viability assay |
Cellular Model | A875 |
Disease | Cancer |