HSPMdb Accession No | HSPMDB000936 |
PMID | 27035072 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | 31 |
IUPAC Name | 1-Benzyl-2-(3,5-bis(trifluoromethyl)phenyl)-1H-imidazo[4,5-f ]-[1,10]phenanthroline |
SMILES | FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nc3c4cccnc4c5ncccc5c3n2Cc6ccccc6 |
Class | Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline |
GI50 (µM) | 2.8 |
Cellular assay | Resazurin based viability assay |
Cellular Model | MCF7 |
Disease | Cancer |