HSPMdb Accession NoHSPMDB000934
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name25
IUPAC Name1-(4-Carboxamidobenzyl)-6,9-dimethoxy-2-phenyl-1H-phenanthro[9,10-d]imidazole
SMILESCOC1=CC2=C(C=C1)C1=C(N(CC3=CC=C(C=C3)C(N)=O)C(=N1)C1=CC=CC=C1)C1=C2C=C(OC)C=C1
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)>10
Cellular assay Resazurin based viability assay
Cellular ModelMCF7
DiseaseCancer

Structure



HSPMDB000934

25

Physicochemical Properties