HSPMdb Accession NoHSPMDB000933
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name23
IUPAC Name1-(4-Carboxamidobenzyl)-2-(4-methoxyphenyl)-1H-phenanthro-[9,10-d]imidazole
SMILESCOC1=CC=C(C=C1)C1=NC2=C(N1CC1=CC=C(C=C1)C(N)=O)C1=C(C=CC=C1)C1=C2C=CC=C1
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)>10
Cellular assay Resazurin based viability assay
Cellular ModelMCF7
DiseaseCancer

Structure



HSPMDB000933

23

Physicochemical Properties