HSPMdb Accession NoHSPMDB000931
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name16
IUPAC Name2,4,5-Tri(4-fluorophenyl)-1H-imidazole
SMILESFc1ccc(cc1)c2[nH]c(c3ccc(F)cc3)c(n2)c4ccc(F)cc4
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)>10
Cellular assay Resazurin based viability assay
Cellular ModelMCF7
DiseaseCancer

Structure



HSPMDB000931

16

Physicochemical Properties