HSPMdb Accession NoHSPMDB000921
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name22
IUPAC Name1-(4-Carboxamidobenzyl)-2-(4-fluorophenyl)-1H-phenanthro-[9,10-d]imidazole
SMILESNC(=O)C1=CC=C(CN2C(=NC3=C2C2=C(C=CC=C2)C2=C3C=CC=C2)C2=CC=C(F)C=C2)C=C1
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)5.9
Cellular assay Resazurin based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB000921

22

Physicochemical Properties