HSPMdb Accession NoHSPMDB000919
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name20
IUPAC Name1-Benzyl-2-(3,5-bis(trifluoromethyl)phenyl)-1H-phenanthro-[9,10-d]imidazole
SMILESFC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nc3c4ccccc4c5ccccc5c3n2Cc6ccccc6
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)>20
Cellular assay Resazurin based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB000919

20

Physicochemical Properties