HSPMdb Accession No | HSPMDB000916 |
PMID | 27035072 |
Target | Hsp70 |
HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
Organism | Human |
Localization | Cytosol and nucleus |
Cellular activity | Antiproliferative activity |
Compound Name | 16 |
IUPAC Name | 2,4,5-Tri(4-fluorophenyl)-1H-imidazole |
SMILES | Fc1ccc(cc1)c2[nH]c(c3ccc(F)cc3)c(n2)c4ccc(F)cc4 |
Class | Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline |
GI50 (µM) | 9.5 |
Cellular assay | Resazurin based viability assay |
Cellular Model | HCT116 |
Disease | Cancer |