HSPMdb Accession NoHSPMDB000913
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name13
IUPAC Name2-(3,5-Bis(trifluoromethyl)phenyl)-6,9-dimethoxy-1H-phenanthro[9,10-d]imidazole
SMILESCOc1ccc2c3[nH]c(nc3c4ccc(OC)cc4c2c1)c5cc(cc(c5)C(F)(F)F)C(F)(F)F
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)11.2
Cellular assay Resazurin based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB000913

13

Physicochemical Properties