HSPMdb Accession NoHSPMDB000912
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name12
IUPAC Name6,9-Dimethoxy-2-phenyl-1H-phenanthro[9,10-d]imidazole
SMILESCOc1ccc2c3[nH]c(nc3c4ccc(OC)cc4c2c1)c5ccccc5
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)7.8
Cellular assay Resazurin based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB000912

12

Physicochemical Properties