HSPMdb Accession NoHSPMDB000909
PMID27035072
TargetHsp70
HSP NameHsc70 (HSPA8) and Hsp72 (HSPA1A)
OrganismHuman
LocalizationCytosol and nucleus
Cellular activityAntiproliferative activity
Compound Name7b
IUPAC Name2-(4-Fluorophenyl)-1H-phenanthro[9,10-d]imidazole
SMILESFc1ccc(cc1)c2[nH]c3c4ccccc4c5ccccc5c3n2
Class Phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthroline
GI50 (µM)6.7
Cellular assay Resazurin based viability assay
Cellular ModelHCT116
DiseaseCancer

Structure



HSPMDB000909

7b

Physicochemical Properties