| HSPMdb Accession No | HSPMDB000906 |
| PMID | 24548239 |
| Target | Hsp70 |
| HSP Name | Hsc70 (HSPA8) and Hsp72 (HSPA1A) |
| Organism | Human |
| Localization | Cytosol and nucleus |
| Cellular activity | Antiproliferative activity |
| Compound Name | 27h |
| IUPAC Name | 2-amino-N-(3-{[2-(4-methylpiperazin-1-yl)-4-[(pyridin-4-yl)methoxy]pyrimidin-5-yl]sulfanyl}phenyl)acetamide |
| SMILES | CN1CCN(CC1)C1=NC=C(SC2=CC=CC(NC(=O)CN)=C2)C(OCC2=CC=NC=C2)=N1 |
| Class | 2,5-Thiodipyrimidine and 5-(Phenylthio) pyrimidine acrylamide |
| GI50 (µM) | 10.7 |
| Site of Interaction | Nucleotide binding domain (allosteric site) |
| Cellular assay | Alamar Blue viability assay |
| Cellular Model | Kasumi-1 |
| Disease | Cancer |
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